Laboratory of Neuroinformatics

dwojcik-lab

Group photo, January 2013. From left: Piotr Majka, Helena Głąbska, Jakub Kowalski, Daniel Wójcik, Szymon Łęski, Jacek Rogala, Chaitanya Chintaluri

Research profile

The main activity of the group is development of tools and models, and putting them to use to understand neural processing of sensory information. We focus on functioning of early levels of sensory systems, in particular thalamo-cortical loop, but we also study the extrageniculate pathway of the visual system and the activity in nucleus accumbens. We analyze and model electrophysiological, behavioral and imaging data. An important part of our activity is the development of a neuroinformatics infrastructure for storage and processing of histological information and the creation of histology-based 3D brain atlases from different input sources (http://www.3dbar.org/).

Methods

• standard statistical frameworks
• nonlinear techniques and machine learning
• Matlab, Python for most data analysis
• open software (Linux, Python, Neuron, VTK, Plone)

Current research activities

• development of methods to reconstruct Current Source Density reliably in different experimental settings from local field potentials
• information processing in the cortico-thalamic part of the rat’s somatosensory system, modeling and analysis of local field potentials
• the role of extrageniculate visual pathway in movement perception, modeling and analysis of spiking activity
• development of databases to store digital representations of histology data and tools for creation of histology-based 3D brain atlases

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